It was a good day for the Arsenal fans after the Gunners cruised to a 3-1 win over their bitter rivals Tottenham Hotspur in the NLD.
With Arsenal taking an early lead courtesy of Thomas Partey's brilliant goal, Kane equalised after Richarlison won a penalty for Spurs.
The Spurs forward already boasts the record for most North London derby goals scored, extending that to 14 this afternoon.
Kane's strike was his 44th against London clubs during his PL career, moving him to the top of the list ahead of Arsenal legend Thierry Henry.
Kane matched Henry’s 43 with a goal against Fulham on September 9 and has now moved ahead with the Gunners legend in attendance.
Kane's 14 is also more than any other player has managed to score against the Gunners in the Premier League era.
His seven penalties scored against Arsenal is also a joint-record for the most scored by one player against a specific opponent.
On top of that, the goal saw Kane become the first player to net 100 times away from home in the Premier League.
The 29-year-old is six clear of Manchester United legend Wayne Rooney on this list, with all-time PL top scorer Alan Shearer in third.
Despite these records, Arsenal took control of the contest in the second half with goals from Gabriel Jesus and Granit Xhaka.