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2025 NFL season serves up one of its biggest matchups in Week 2 as the Kansas City Chiefs host the Philadelphia Eagles at Arrowhead Stadium. This marks the first meeting between the two teams since Super Bowl 58, where the Eagles claimed a decisive 40-22 victory. With both sides entering the season as top contenders, anticipation is building for this early-season clash.
When and where to watch
Fans won’t want to miss the action from Arrowhead Stadium on Sunday, September 14. Kickoff is scheduled for 1 p.m. ET.
TV: FOX
Streaming: Fubo
Follow along: CBS Sports App
Betting odds and lines
According to the SportsLine consensus, the Eagles are slight favorites heading into the contest.
Spread: Eagles -1
Over/Under: 47 points
Moneyline: Eagles -115 (risk $115 to win $100), Chiefs -104
The narrow odds reflect just how evenly matched these two franchises are. Arrowhead remains one of the toughest venues in football, but Philadelphia comes in with momentum after opening their campaign with a gritty win.
Eagles’ strong start
The Eagles opened their season with a 24-20 victory over the Dallas Cowboys, showcasing resilience on both sides of the ball. Quarterback Jalen Hurts did not throw a touchdown pass but made his presence felt with two rushing scores.
One of the biggest questions surrounding Philadelphia entering 2025 was its defense, particularly after offseason departures. However, holding Dallas scoreless in the second half proved they remain a formidable unit. That defensive performance could be crucial against Patrick Mahomes and one of the league’s most dangerous offenses.
Chiefs seeking redemption
On the other side, the Chiefs enter Week 2 determined to rebound after a 27-21 loss to the Los Angeles Chargers in the NFL São Paulo Game. Kansas City’s defense struggled against Justin Herbert, who threw three touchdown passes, while Quentin Johnston and Keenan Allen proved difficult to contain.
Still, history suggests betting against Kansas City is risky. The Chiefs were 12-0 in one-point games last season, highlighting their ability to thrive in tight situations. With Mahomes leading the charge and Travis Kelce anchoring the offense, the reigning champions will aim to turn things around quickly.
Model prediction
According to the SportsLine Projection Model, Philadelphia holds a slim edge in this matchup. The model forecasts that the Eagles will cover the spread in 51% of simulations. Last season, the Eagles were more reliable against the spread (14-7 ATS) compared to the Chiefs (9-11 ATS).
With Philadelphia’s defense showing early strength and Kansas City under pressure to avoid a second straight loss, this Super Bowl rematch is shaping up to be one of the most closely contested games of the season.
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